You're asking about **1-[2-[2-(2,3-dihydro-1H-inden-5-yloxy)ethoxy]ethyl]-1,2,4-triazole**. This is a complex organic molecule, and to understand its importance in research, let's break down its structure and potential applications:
**Structure:**
* **1,2,4-triazole:** This is a heterocyclic ring system containing nitrogen atoms. It's a common building block in many pharmaceuticals and agrochemicals.
* **2,3-dihydro-1H-inden-5-yloxy:** This refers to a modified indene molecule, a bicyclic ring system. The 5-yloxy part means an oxygen atom is attached at the 5th position on the indene ring.
* **Ethoxy:** This refers to an ethyl group (CH3CH2-) attached to an oxygen atom (-O-).
**Overall, this molecule is essentially a 1,2,4-triazole with a long, flexible chain attached. This chain incorporates an indene derivative.**
**Why it might be important in research:**
This type of molecule, with its unique structure, could be explored in several research areas:
* **Pharmacology:**
* **Drug Discovery:** The combination of a triazole ring and an indene derivative can lead to a molecule with potentially interesting biological activity. Triazoles are known for their diverse pharmacological properties, and indene derivatives have been studied for their potential anti-inflammatory and anticancer effects. This molecule could be a starting point for developing new drugs.
* **Drug Delivery:** The long, flexible chain could act as a linker to attach the triazole to other molecules, creating a drug conjugate. This could be used to deliver drugs to specific targets in the body or to improve their absorption and bioavailability.
* **Material Science:**
* **Polymer Chemistry:** Triazoles are often used in click chemistry, a powerful tool for building polymers. This molecule could be incorporated into polymers to create materials with specific properties.
* **Organic Electronics:** Indene derivatives have shown promise in organic electronics. This molecule could be investigated for its potential use in organic solar cells or other electronic devices.
**Important Notes:**
* **This is a hypothetical molecule:** I haven't found any specific information about its synthesis or biological activity. It's likely that the molecule has not been extensively studied yet.
* **Further Research:** To fully understand the importance of this molecule, further research would be needed. Researchers would need to synthesize the molecule, test its properties, and explore its potential applications.
**To get more information about this molecule, you would need to:**
* **Consult a chemical database:** Databases like PubChem, SciFinder, or Reaxys might have information on the molecule's synthesis, properties, or related compounds.
* **Search for relevant scientific literature:** Look for papers that discuss the synthesis and properties of triazoles and indene derivatives. This could lead you to information about similar molecules that have been studied.
I hope this explanation helps! Let me know if you have any further questions.
ID Source | ID |
---|---|
PubMed CID | 2199754 |
CHEMBL ID | 1359325 |
CHEBI ID | 121607 |
Synonym |
---|
MLS000049305 |
smr000075150 |
1-{2-[2-(2,3-dihydro-1h-inden-5-yloxy)ethoxy]ethyl}-1h-1,2,4-triazole |
CHEBI:121607 |
1-[2-[2-(2,3-dihydro-1h-inden-5-yloxy)ethoxy]ethyl]-1,2,4-triazole |
HMS2314K21 |
CHEMBL1359325 |
Q27210167 |
SR-01000270997-1 |
sr-01000270997 |
Class | Description |
---|---|
indanes | |
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
---|---|---|---|---|---|---|---|
Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 79.4328 | 0.0447 | 17.8581 | 100.0000 | AID485294 |
15-lipoxygenase, partial | Homo sapiens (human) | Potency | 7.9433 | 0.0126 | 10.6917 | 88.5700 | AID887 |
TDP1 protein | Homo sapiens (human) | Potency | 23.1093 | 0.0008 | 11.3822 | 44.6684 | AID686978 |
aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 15.8489 | 0.0112 | 12.4002 | 100.0000 | AID1030 |
chromobox protein homolog 1 | Homo sapiens (human) | Potency | 79.4328 | 0.0060 | 26.1688 | 89.1251 | AID540317 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID1745845 | Primary qHTS for Inhibitors of ATXN expression | |||
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | |||
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 3 (60.00) | 24.3611 |
2020's | 1 (20.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.56) All Compounds (24.57) |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |